08/26/2024, 03:59 PM UTC
利用HA/CeO2纳米粒子靶向递送姜黄素Targeted Delivery of Curcumin Using HA/CeO2 Nanoparticles
➀ 研究人员开发了负载姜黄素的HA/CeO2纳米粒子，以提高姜黄素的疗效，解决其溶解性差和生物利用度低的问题。➁ 这些纳米粒子显示出均匀的尺寸分布和高包封效率，有助于有效地递送到发炎组织。➂ 体外和体内研究表明，这些纳米粒子在治疗炎症性肠病等疾病方面具有潜力，姜黄素的持续释放和炎症减轻。➀ Researchers developed curcumin-loaded HA/CeO2 nanoparticles to improve curcumin's therapeutic efficacy, addressing its poor solubility and low bioavailability. ➁ The nanoparticles showed a uniform size distribution and high encapsulation efficiency, facilitating effective delivery to inflamed tissues. ➂ In vitro and in vivo studies demonstrated the nanoparticles' potential in treating diseases like inflammatory bowel disease, with sustained curcumin release and reduced inflammation.
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