02/18/2025, 03:51 PM UTC
靶向大脑的信使RNA递送新平台前景广阔Promising New Platform for Brain-Targeted mRNA Delivery
➀ 纽约西奈山伊坎医学院的研究人员开发了一种脂质纳米颗粒系统,能够将信使RNA递送到大脑;
➁ 该系统能够绕过血脑屏障,并可能治疗药物成瘾和阿尔茨海默病等疾病;
➂ 研究表明,这些脂质纳米颗粒可以安全有效地将mRNA递送到大脑,为基于mRNA的神经和精神疾病治疗开辟了机会。
➀ Researchers at the Icahn School of Medicine at Mount Sinai have developed a lipid nanoparticle system capable of delivering mRNA to the brain;
➁ This system bypasses the blood-brain barrier and could potentially treat conditions like drug addiction and Alzheimer's disease;
➂ The study shows that the lipid nanoparticles can safely and efficiently deliver mRNA into the brain, opening opportunities for mRNA-based therapies for neurological and psychiatric disorders.
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