<p>➀ Traditional biosensors face challenges in blood due to rapid degradation, limiting real-time monitoring capabilities;</p><p>➀ Researchers developed the SENSBIT system, inspired by the gut's protective structure, using a 3D nanoporous gold surface and mucosal-like coating for enhanced stability;</p><p>➂ The sensor retained over 70% signal after a month in human serum and functioned for a week in live rats, enabling early infection detection and advancing personalized healthcare.</p>