01/28/2025, 12:54 PM UTC
ALD和Parylene-ALD涂层在神经植入物中的生物稳定性Biostability of ALD and Parylene-ALD Coatings in Neural Implants
➀ 最近一篇发表在Small的文章讨论了神经植入物微封装的挑战，重点关注ALD和Parylene-ALD涂层的生物稳定性。
➁ 研究人员使用动物模型进行了为期七个月的体内研究，评估了铪基ALD涂层和结合了Parylene C与钛基ALD层的有机-无机混合涂层的生物稳定性。
➂ 研究发现，铪基ALD涂层对离子渗透表现出显著的耐受性，而混合涂层则显示出明显的降解，这突显了对于长期生物相互作用仔细选择材料的重要性。
➀ A recent article in Small discusses the challenges in micro-packaging for neural implants, focusing on the biostability of ALD and Parylene-ALD coatings.
➁ Researchers conducted a seven-month in vivo study using animal models to evaluate the biostability of hafnium-based ALD coatings and a hybrid organic-inorganic stack combining Parylene C with titanium-based ALD layers.
➂ The study found that hafnium-based ALD coatings demonstrated impressive resilience against ionic penetration, while the hybrid coating showed considerable degradation, highlighting the need for careful material selection for long-term biological interactions.
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