04/24/2025, 12:30 PM UTC
纳米碟靶向胆固醇以对抗侵袭性脑瘤Nanodiscs Target Cholesterol to Fight Aggressive Brain Tumor
➀ 密歇根大学的科研人员开发了靶向GBM肿瘤胆固醇水平的纳米碟，这种治疗方法有望提高治疗小鼠的生存率；
➁ 目前GBM的治疗方法包括手术、放疗和化疗，但尚无治愈方法；
➂ 纳米碟递送LXR激动剂，增加细胞泵以去除胆固醇，导致癌细胞破坏，并刺激免疫系统靶向肿瘤。
➀ Researchers at the University of Michigan developed nanodiscs to target cholesterol levels in GBM tumors, showing promise in increasing survival rates in treated mice;
➁ Current treatment limitations for GBM include surgery, radiation, and chemotherapy, with no cure available;
➂ The nanodiscs deliver LXR agonists to increase cellular pumps for cholesterol removal, leading to cancer cell destruction, and stimulate the immune system to target tumors.
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