06/12/2024, 09:19 PM UTC
酶-纳米杂化方法有效清除生物膜Enzyme-Nanohybrid Approach Elicits Strong Biofilm Eradication
1、中国科学院福建物质结构研究所的陈学元教授团队开发了一种针对小鼠铜绿假单胞菌生物膜诱导的肺部感染的无创光热治疗技术。2、该团队创新性地制备了具有近红外II区发光和高光热转换效率的Aly-NaNdF4纳米杂化物。3、这些纳米杂化物显示出强大的生物膜清除能力，并在肝脏和脾脏中代谢，避免了长期毒性。1. A research team from FJIRSM, CAS, led by Prof. Chen Xueyuan, developed noninvasive phototheranostics for Pseudomonas aeruginosa biofilm-induced pulmonary infection in mice. 2. The team created novel Aly-NaNdF4 nanohybrids with NIR-II luminescence and excellent photothermal conversion efficiency. 3. These nanohybrids demonstrated strong biofilm eradication and were metabolized in the liver and spleen, avoiding long-term toxicity.
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