10/25/2024, 06:10 PM UTC
纳米PROTACs在结直肠癌治疗中的应用进展Advancing Colorectal Cancer Treatment with Nano-PROTACs
➀ 研究引入基于聚合物的纳米PROTACs，以改善结直肠癌治疗的递送和疗效；➁ 研究表明，PSRNs在肿瘤组织中的增强渗透和保留效应，提高了治疗潜力；➂ 体内研究表明，PSRNs与免疫检查点抑制剂联合使用可显著提高生存率。➀ The research introduces polymer-based nano-PROTACs to improve the delivery and efficacy of treatments for colorectal cancer; ➁ The study demonstrates the enhanced permeation and retention effect of PSRNs in tumor tissues, leading to increased therapeutic potential; ➂ In vivo studies show improved survival rates with PSRNs combined with immune checkpoint inhibitors.
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