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➀ Researchers developed **PPBC LNPs**, multifunctional nanoparticles integrating photodynamic therapy (PDT), photothermal therapy (PTT), and real-time imaging to combat treatment-resistant bladder cancer;

➁ The nanoparticles demonstrated strong anti-cancer effects by inducing cell death and suppressing autophagy (a resistance mechanism) while enabling high-resolution imaging via photoacoustic and fluorescence modalities;

➂ In vivo trials showed tumor reduction with no toxicity, and scalable microfluidic synthesis supports potential clinical translation for precision medicine.

➀ Researchers discovered that the internal shape of lipid nanoparticles (e.g., cubosomes vs. liposomes) significantly impacts cellular uptake efficiency, with cubosomes showing 8x higher cell entry than commonly used liposomes;

➁ Cubosomes bypass traditional active cellular pathways (like endocytosis), fusing directly with cell membranes to evade degradation, enhancing mRNA drug delivery potential;

➂ The findings pave the way for designing tailored nanoparticles to improve precision in targeting tissues and diseases, with future research focusing on in vivo behavior and therapeutic applications.

➀ PI unveiled advanced industrial-grade solutions at LASER World of PHOTONICS 2025, including the AI-driven F-141 PINovAlign 6-axis alignment system for high-volume photonics and semiconductor manufacturing.

➁ The H-815 hexapod and B-421 BIX nanopositioning stages were highlighted for their robustness, compact design, and precision, targeting 24/7 industrial automation in photonics and semiconductor sectors.

➂ Future technologies like magnetic levitation (MagLev) stages and novel hexapod concepts showcased PI’s innovation in picometer-level precision and high-speed applications.

➀ PI introduces PICMA® Plus piezo actuators offering increased displacement up to 43 microns while retaining high stiffness and reliability;

➁ Utilizes space-tested ceramic encapsulation for extreme durability, validated by NASA/JPL’s 100 billion cycle test in Mars rover missions;

➂ Operates in temperatures from -40°C to 200°C, targeting industries like semiconductor testing, photonics, and biotechnology.

➀ Scientists used a 12-nanometer X-ray beam to non-destructively analyze ultra-thin nanosheets in electronics, revealing deformation mechanisms;

➁ The study identified two competing deformation mechanisms: long-range lattice mismatch and short-range layering effects near edges;

➂ These insights aid in optimizing nanostructures for next-gen microelectronics like GAAFETs, enhancing device performance prediction.

➀ A non-destructive X-ray imaging method with a 12-nm beam analyzed structural deformations in nanosheets used in Gate-All-Around Field Effect Transistors (GAAFETs);

➁ Two deformation mechanisms were identified: long-range (lattice mismatch and edge relaxation) and short-range (linked to nanosheet layering);

➂ IBM and Brookhaven's NSLS-II collaboration provides insights to enhance reliability and performance prediction for nanoscale electronics.

➀ Researchers at IISc developed a vanadium-based nanozyme to combat abnormal blood clotting by mimicking antioxidant enzymes and reducing reactive oxygen species (ROS) levels;

➁ The V₂O₅ nanozymes effectively suppressed platelet overactivation in human blood and reduced thrombosis in a mouse model of pulmonary thromboembolism (PTE) without harmful side effects;

➂ Unlike traditional antiplatelet drugs, the nanozymes modulate redox signaling without interfering with normal clotting, potentially reducing bleeding risks associated with current therapies.

➀ Loughborough University physicists created a platinum violin measuring 35 microns long using nanotechnology to demonstrate their new nanolithography system's capabilities;

➁ The process involved thermal scanning probe lithography with a NanoFrazor machine, depositing platinum on a resist-coated chip to form the microscopic structure;

➂ The system supports research into advanced materials for next-gen computing, including energy-efficient data storage and processing methods.

➀ The study introduces a biomimetic nanovaccine (AECM@PC7A) that combines IFN-γ-treated tumor cell membranes with a synthetic adjuvant (PC7A) to enhance neoantigen presentation and activate the STING pathway, addressing limitations of conventional cancer vaccines;

➁ In preclinical models, the vaccine triggered robust T-cell responses, reduced tumor growth and metastasis, and demonstrated synergy with immune checkpoint inhibitors, leading to prolonged survival and immune memory;

➂ The platform offers a scalable approach for personalized immunotherapy by leveraging tumor-specific neoantigens and simplified manufacturing processes, showing promise for clinical translation.

➀ An international team led by Rice University synthesized glaphene, a hybrid 2D material combining graphene and silica glass, exhibiting unique semiconductor properties.

➁ The synthesis involved a custom high-temperature process, leading to stronger interlayer interactions and novel electronic behaviors.

➂ The breakthrough highlights the potential for creating tailored hybrid materials for advanced electronics and quantum devices through cross-disciplinary collaboration.

➀ 2D materials like graphene and TMDs exhibit properties mimicking biological neural functions, enabling energy-efficient neuromorphic devices for AI and robotics;

➁ Recent studies showcase 2D materials' versatility in optical signal processing, multi-sensory simulations (e.g., taste, smell), and integrated neural networks with ultra-low power consumption;

➂ Challenges in scalable manufacturing, defect-free synthesis, and system integration must be addressed to transition lab innovations into commercial AI hardware and sensory technologies.

➀ The L-511 precision linear stage by PI delivers ultra-fine resolution down to 0.005 microns with linear encoders, supports multi-axis configurations, and handles loads up to 110 lbs (500 N) for high stability;

➀ Customizable 2-axis/3-axis assemblies and motor controllers, paired with PI's software suite, enable seamless integration into automated systems;

➂ Widely used in semiconductor manufacturing, biotech, metrology, and laser processing for precision alignment and automation efficiency.

➀ A study demonstrates that incorporating polymorphic FAPbI₃ perovskite nanofillers into PVDF films via 3D printing enhances triboelectric nanogenerator (TENG) performance;

➁ Annealing triggers a phase transition from δ to α-phase FAPbI₃, increasing PVDF’s β-phase content (up to 83%) and creating mesoporous structures for higher charge density;

➂ Resulting TENGs achieve 392 V peak-to-peak voltage and 2587 μW/cm² power density, offering scalable, sustainable energy solutions for microelectronics.

➀ This study presents a composite wound dressing made from polylactic acid (PLA), curcumin, and carbon nanotubes (CNTs) designed to enhance mechanical strength and antibacterial activity.

➁ Electrospinning was used to fabricate the dressing, with CNTs incorporated to enhance curcumin release and antibacterial effectiveness.

➂ The results showed that the addition of CNTs significantly improved mechanical strength and thermal stability, and the dressing exhibited good antibacterial activity.

➀ Researchers at the University of Michigan developed nanodiscs to target cholesterol levels in GBM tumors, showing promise in increasing survival rates in treated mice;

➁ Current treatment limitations for GBM include surgery, radiation, and chemotherapy, with no cure available;

➂ The nanodiscs deliver LXR agonists to increase cellular pumps for cholesterol removal, leading to cancer cell destruction, and stimulate the immune system to target tumors.

➀ British climate tech company Levidian and Canadian graphene technology company Zentek have entered an agreement to explore the establishment of a new manufacturing facility in the Middle East.

➁ The collaboration aims to combine expertise in carbon capture, graphene production, and materials development to accelerate the roll out of Zentek’s ZenGUARD™ Enhanced Air Filters and other graphene-enhanced products.

➂ Levidian’s patented LOOP system produces clean hydrogen and high-quality graphene by capturing carbon from methane before it’s burned.

➀ A new fabrication method for nonlinear optical components using nanostructured polycrystalline lithium niobate (LN) is reported;

➁ The method addresses limitations of top-down fabrication techniques for LN;

➂ It introduces a bottom-up strategy using sol-gel chemistry to produce a printable LN precursor;

➃ The resulting polycrystalline LN maintains relevant optical properties and allows for the fabrication of nonlinear metasurfaces.

➀ A recent study introduces a self-aligned gate architecture for carbon nanotube (CNT) phototransistors designed for shortwave infrared (SWIR) detection.

➁ The devices demonstrate high responsivity and detectivity while maintaining a simplified fabrication process.

➂ The self-aligned gate structure allows for complete coverage of the CNT channel, improving optical and electrical coupling.

➀ PI (Physik Instrumente) is expanding its US manufacturing capabilities to address trade dynamics and improve customer support.

➁ The new facility in Shrewsbury, Massachusetts, is set to open in Fall 2025.

➂ The expansion aims to reduce lead times and align production closer to the US customer base.

➀ This research investigates how metallic thin films, specifically cobalt layers used in hard disk drives (HDDs), can be modified to improve performance and reliability through plasma-assisted surface modification techniques.

➁ The study uses molecular dynamics (MD) simulations and experimental validation to demonstrate how different inert gas ions affect asperity size and surface texture.

➂ The findings suggest that heavier inert gas ions are more effective at reducing asperity size, with Xenon (Xe) providing the most pronounced smoothing effect.

➀ Researchers from the University of Connecticut and Eascra Biotech are producing innovative nanomaterials in space to improve treatments for osteoarthritis and cancer.

➁ Janus base nanomaterials (JBNs) are developed to regenerate cartilage and could be used in precision cancer treatment.

➂ The ISS National Lab is used to test the production of JBNs in space, where gravity-driven forces are reduced, leading to better uniformity and patient outcomes.

Thermic Edge Ltd proudly introduces its new Atomic Layer Deposition (ALD) System, designed to accelerate the integration of 2D materials into next-generation semiconductor devices. The system combines single-chamber ALD and high-temperature annealing, reducing contamination risks and improving process efficiency. It supports wafer-scale processing up to 8 inches and ensures uniform deposition across large-area substrates. The system features a showerhead gas delivery system for uniform gas distribution, precise temperature control, and multi-gas compatibility for oxide, sulfide, and nitride processing.

➀ Researchers have developed a new approach to model seed particles with 100 to 200 atoms;

➁ The shapes of the tiny particles depend on the solvent composition and temperature;

➂ This research can suggest promising routes for growing nanoparticles with desired sizes and shapes.

➀ Melexis, a global supplier of micro-electronic semiconductor solutions, announces a significant expansion in its China strategy by establishing a local logistics hub and end-to-end local manufacturing in China.

➁ The expansion is in response to the rapid growth of China's automotive, consumer, industrial, and robotics industries, where Melexis has secured notable design wins.

➂ Melexis has entered a new phase of its China strategy, focusing on innovation and customer collaboration, while reducing lead times.

➀ This study explores the development of chitosan-silanized hexagonal boron nitride (hBN) nanocomposite films;

➁ It focuses on their structural, mechanical, and barrier properties;

➂ The research aims to enhance the performance of biodegradable polymer films, overcoming limitations of chitosan.

➀ Researchers have developed a molecular nanocage that can capture a wide range of PFAS from water, significantly outperforming conventional filtration methods like activated carbon.

➁ The nanocage system removed 80% of PFAS from sewage and 90% from groundwater in study tests.

➂ The material shows promise for more efficient, safer, and sustainable water remediation.

➀ A study in Scientific Reports introduces the development of PVA films embedded with biochar-modified titanium dioxide nanocomposites for improved water treatment performance;

➁ The research aims to address dye removal and disinfection challenges in wastewater management through the use of TiO₂ and biochar;

➂ The biochar-modified nanocomposites demonstrate high adsorption capacity, rapid dye removal, and antibacterial properties, making them suitable for wastewater treatment.

➀ Researchers at Argonne National Laboratory have discovered how to use light to control the symmetry of quantum dots, leading to new materials with tailored properties;

➁ The study demonstrates that light can alter the arrangement of atoms in quantum dots, changing their electronic properties;

➂ The findings open up new possibilities for designing materials with unique properties, potentially revolutionizing fields like electronics and medical imaging.

➀ The article introduces a dual-mode film made from nano-engineered scattering fibers derived from upcycled chip bags, designed for sustainable thermal management.

➁ The film absorbs solar energy in cold conditions and reflects it in warm ones, improving building energy efficiency.

➂ The film is constructed with a biopolymer base and silica nanoparticles, and its scalability and environmental responsibility are highlighted.

➀ Researchers from Oregon State University have developed a method to deliver anti-inflammatory drugs across the blood-brain barrier;

➁ This may enable new treatments for diseases such as cancer cachexia, multiple sclerosis, Parkinson’s disease, and Alzheimer's disease;

➂ The delivery system uses specially designed nanoparticles and has been successful in a mouse model.